A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/35 (2006.01) A61K 31/535 (2006.01)
Patent
CA 2349402
The invention relates to a composition comprising a first component (a) which is (R)-3-N,N-dicyclobutylamino-8-fluoro-3,4-dihydro-2H-1-benzopyran-5- carboxamide in the form of the free base, pharmaceutically acceptable salts and/or solvates thereof, and a second component (b) which is a monoamine oxidase (MAO) inhibitor in the form of the free base, pharmaceutically acceptable salts and/or solvates thereof, the preparation thereof, pharmaceutical formulations containing said composition, a kit containing said composition, use of and a method of treatment of affective disorders such as mood disorders and anxiety disorders with said composition.
L'invention concerne une composition contenant un premier composant (a): le (R)-3 N,N-dicyclobutylamino-8-fluoro-3,4-dihydro-2H-1-benzopyrane-5-carboxamide sous la forme d'une base libre et des sels pharmaceutiquement acceptables et/ou des solvats dudit composant; un second composant (b) inhibiteur de la monoamine oxydase (MAO) sous la forme d'une base libre et des sels pharmaceutiquement acceptables et/ou des solvats dudit composant ainsi que leur préparation. L'invention concerne en outre des formulations pharmaceutiques et une trousse contenant cette composition ainsi que leur utilisation, et des méthodes de traitement de troubles affectifs, tels que les troubles de l'humeur et les troubles anxieux, au moyen de cette composition.
Ross Svante
Thorberg Seth-Olov
Astrazeneca Ab
Fetherstonhaugh & Co.
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