A new phenylacetic derivative and process for their obtention

Details A new phenylacetic derivative and process for their obtention A new phenylacetic derivative and process for their obtention

C - Chemistry, Metallurgy

07

C

167/122, 260/514

C07C 229/42 (2006.01) A61K 31/315 (2006.01)

Patent

CA 2017746

A pharmaceutical phenylacetic acid derivative of the following formula (I): (see formula I) The invention also relates to a process for preparing the derivative of formula (I) which includes reacting 2-(2,6-dichloroaniline)-phenylacetic acid with zinc oxide, zinc hydroxides, zinc carbonates or zinc salts or reacting an ammonium salt, an alkali metal salt or an alkaline earth metal salt of 2-(2,6-dichloroaniline)-phenylacetic acid with a zinc salt, e.g. zinc chloride, in a nonpolar solvent. The compound of formula (I) is novel and has improved pharmaceutical properties in anti-inflammatory preparations.

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