A nicotine and/or nicotine metabolite detection system

Details A nicotine and/or nicotine metabolite detection system A nicotine and/or nicotine metabolite detection system

G - Physics

01

N

G01N 33/52 (2006.01) A61K 31/439 (2006.01) A61K 31/44 (2006.01) A61K 31/4425 (2006.01) A61K 31/445 (2006.01) A61K 31/4545 (2006.01) A61K 31/455 (2006.01) A61K 31/465 (2006.01) G01N 31/22 (2006.01) G01N 33/94 (2006.01)

Patent

CA 2133415

PCT/US93/03233 (57) Abstract A solid phase capable of detecting the presence of nicotine and/or nicotine metabolites is described. The solid phase is im- pregnated with assay reagent including a color determinant a buffer. a cyanogen releasing agent and a cyanogen halide forming agent. The solid phase provides a means whereby unprocessed urine samples over a wide range of different pH values can be test- ed for the presence of nicotine and/or nicotine metabolites. The assay results may be determined by direct visualization of the co- lor of the solid phase. Also described are methods of preparating and using the solid phase, and kits containing the solid phase.

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