C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/85 (2006.01) A01K 67/027 (2006.01) A61K 49/00 (2006.01) C07K 14/72 (2006.01)
Patent
CA 2585308
The present invention relates to the field of diseases, such as Alzheimer's disease, where abnormal brain accumulation of ~ amyloid and/or amyloid plaques are involved. More specifically, the present invention relates to a non-human animal model for such diseases and its use in screening methods for molecules for treating same.
La présente invention concerne le domaine des maladies, par exemple la maladie d'Alzheimer, associée à une accumulation anormale de plaques ß amyloïdes et/ou amyloïdes dans le cerveau. L'invention concerne, plus spécifiquement, un modèle animal non humain de maladies de ce type, et son utilisation dans des méthodes de criblage de molécules utilisées dans le traitement de celles-ci.
Bohl Delphine
Carro Eva
Heard Jean-Michel
Torres-Aleman Ignacio
Consejo Superior de Investigaciones Cientificas
Institut National de La Sante Et de La Recherche Medicale (inser
Institut Pasteur
Robic
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