C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/09 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/10 (2006.01) C12P 21/02 (2006.01)
Patent
CA 2679703
The invention provides an extremely useful novel .beta.-galactoside-.alpha.-2,6-sialyltransferase which has an optimum pH for reaction in the neutral to alkaline range, and a nucleic acid encoding the sialyltransferase. The invention also provides a vector containing the nucleic acid encoding the sialyltransferase, a host cell transformed with the vector, and further a method for producing recombinant .beta.-galactoside-.alpha.-2,6-sialyltransferase.
La présente invention concerne une nouvelle .beta.-galactoside .alpha.-2,6-sialyltransférase extrêmement utile qui présente un pH optimum pour la réaction dans la plage neutre à basique, et un acide nucléique codant pour la sialyltransférase. L'invention concerne également un vecteur contenant l'acide nucléique codant pour la sialyltransférase, une cellule hôte transformée avec le vecteur, et en outre un procédé permettant de produire une .beta.-galactoside .alpha.-2,6-sialyltransférase recombinée.
Hamada Yoko
Ichikawa Masako
Kajiwara Hitomi
Mine Toshiki
Takakura Yoshimitsu
Japan Tobacco Inc.
Robic
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