C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2190027
The present invention provides a novel isolated and purified protein that is produced by brain endothelial cells, has a molecular weight of approximately 67 kDa of SDS-PAGE, with the protein being capable of stimulating proliferation of cerebral arteriole smooth muscle cells. Also provided are various methods of using this novel protein or the gene encoding this protein, including methods of treating various cerebrovascular diseases.
Nouvelle protéine isolée et purifiée produite par les cellules endothéliales du cerveau, présentant un poids moléculaire d'environ 67 kDa de SDS-PAGE, et capable de stimuler la prolifération des cellules des muscles lisses des artérioles cérébrales. On décrit également différents procédés d'utilisation de cette nouvelle protéine ou du gène codant cette protéine, ainsi que des procédés de traitement de différentes maladies cérébrovasculaires.
Alam Nargis A.
Alam Syed S.
Yatsu Frank M.
Borden Ladner Gervais Llp
Research Development Foundation
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