A novel cancer drug screen based on cell cycle uncoupling

Details A novel cancer drug screen based on cell cycle uncoupling A novel cancer drug screen based on cell cycle uncoupling

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01) C12N 5/10 (2006.01) C12Q 1/18 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2248935

Checkpoint gene-defective human cells are useful for screening potential anti-tumor agents. Potential therapeutic agents are screened for the ability to cause DNA accumulation or cell death in a checkpoint gene-defective human cell.

Cellules humaines défectives pour le gène de point de contrôle; elles servent au dépistage d'agents antitumoraux potentiels. Dépistage d'agents thérapeutiques potentiels pour déceler leur capacité d'accumulation d'ADN ou leur pouvoir de tuer des cellules dans le cas des cellules humaines défectives pour le gène de point de contrôle.

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