A novel combination of a .beta.-receptor blocker and an opioid

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/485 (2006.01) A61K 31/135 (2006.01) A61K 31/435 (2006.01) A61K 31/445 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2233677

New combination of a .beta.-receptor blocker or a pharmaceutically acceptable salt thereof, and an opioid or a pharmaceutically acceptable salt thereof, optionnally in the presence of a pharmaceutically acceptable carrier or any additional agents which may be active or inactive. The new combination confers a synergistic effect, and provides unexpected efficacy in the treatment of pain.

Cette invention concerne une nouvelle combinaison entre, d'une part, un agent de blocage de beta -récepteur ou l'un de sels acceptable sur le plan pharmaceutique, et d'autre part, un opiacé ou l'un de sels acceptable sur le plan pharmaceutique, et ceci éventuellement en présence d'un véhicule acceptable sur le plan pharmaceutique ou de tout autre agent actif ou inactif. Cette nouvelle combinaison confère des effets synergiques et possède une efficacité étonnante dans le traitement de la douleur.

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