A novel composition for transdermal administration of an...

Details A novel composition for transdermal administration of an... A novel composition for transdermal administration of an...

A - Human Necessities

61

K

A61K 31/57 (2006.01) A61K 9/06 (2006.01) A61K 31/565 (2006.01) A61K 47/10 (2006.01) A61K 47/18 (2006.01) A61K 47/32 (2006.01)

Patent

CA 2207144

Pharmaceutical formulation in the form of a gel suitable for the transdermal administration of an active agent of the class of estrogens or of progestin class or of a mixture of both, comprising: - as permeation enhancers of the above said active agents a combination consisting substantially of an aliphatic alcohol having general formula CH3(CH2)n CH2OH wherein n = 8-16 and of a monoalkylether of diethylene glycol; - as a vehicle or carrier, a combination of an alkanol of 2÷4 C atoms, a glycol and water; - as gelling agent a polymer or copolymer of acrylic acid; - a tertiary amine as a thickening and neutralizing agent.

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