C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 333/64 (2006.01) A61K 31/4535 (2006.01) A61K 31/567 (2006.01) A61K 38/22 (2006.01) A61K 45/06 (2006.01) A61P 9/00 (2006.01) A61P 19/10 (2006.01) A61P 25/00 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2314682
The present invention is directed to a novel crystalline hydrate of 6-hydroxy-3-(4-[2-(piperidin-1- yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene hydrochloride and uses for same, including inhibition of disease states associated with estrogen deprivation including cardiovascular disease, hyperlipidemia, and osteoporosis; and inhibition of other pathological conditions such as endometriosis, uterine fibrosis, estrogen-dependent cancer (including breast and uterine cancer), prostate cancer, benign prostatic hyperplasia, CNS disorders including Alzheimer's disease, prevention of breast cancer, and up-regulating ChAT.
Bush Julie Kay
Conrad Preston Charles
Flom Merlyn Gerard
Luke Wayne Douglas
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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