A novel family of beta sub-unit proteins from a...

Details A novel family of beta sub-unit proteins from a... A novel family of beta sub-unit proteins from a...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2371976

The present invention relates to a novel family of beta sub-unit proteins from a voltage-gated sodium channel, and particularly the human and the rat beta sub-units which have been collectively identified as .beta.3, in view of their close structural relationship. The invention also deals with the use of the .beta.3 sub-unit polypeptide or a fragment thereof as well as of the nucleic acids encoding same for therapeutic, diagnostic and screening purposes.

L'invention porte sur une nouvelle famille de protéines sous-unité .beta. du canal sodique potentio-dépendant et en particulier sur les sous-unités de l'homme et du rat désignées collectivement par .beta.3 en raison de leur structure très voisine. L'invention porte également sur l'utilisation des polypeptides sous-unité .beta.3 (ou de leurs fragments) et sur les acides nucléiques codant pour elles, à des fins thérapeutiques, diagnostiques ou de criblage.

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