C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 45/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2451686
Novel GAVE3 polypeptides, proteins and nucleic acid molecules are provided. In addition to isolated, full-length GAVE3 proteins, isolated GAVE3 fusion proteins, antigenic peptides and anti-GAVE3 antibodies are taught. GAVE3, recombinant expression vectors, host cells into that the expression vectors have been introduced and non-human transgenic animals in that a GAVE3 gene has been introduced or disrupted are taught. Diagnostic, screening and therapeutic methods utilizing compositions of the invention also are provided.
L'invention se rapporte à de nouveaux polypeptides, protéines et molécules d'acide nucléique GAVE3. L'invention concerne également, outre des protéines GAVE3 pleine longueur isolées, des protéines de fusion GAVE3 isolées, des peptides antigéniques et des anticorps anti-GAVE3. L'invention concerne également GAVE3, des vecteurs d'expression recombinants, des cellules hôtes dans lesquelles les vecteurs d'expression ont été introduits et des animaux transgéniques non humains dans lesquels un gène GAVE3 a été introduit ou dissocié. L'invention a également trait à des procédés de diagnostic, de criblage et de thérapie utilisant les compositions de l'invention.
Ardati Ali
Eishingdrelo Haifeng
Jupp Ray
Minnich Anne
Ni Donghui
Aventis Pharmaceuticals Inc.
Bereskin & Parr
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