A novel human card-only protein that inhibits pro-il-1beta...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/47 (2006.01) C12N 15/12 (2006.01) C12N 15/15 (2006.01)

Patent

CA 2568161

The present invention relates to a novel member of the card protein family. More specifically, it relates to a novel human card-only protein. The invention relates further to the use of this protein to inhibit pro- interleukin-1.beta. maturation, preferably without inducing NF-KB activity or apoptosis.

La présente invention concerne un nouveau membre de la famille des protéines CARD. L'invention concerne plus précisément une nouvelle protéine humaine présentant des homologies avec CARD. L'invention concerne également l'utilisation de cette protéine pour inhiber la maturation de la pro-interleukine-1.beta., de préférence sans induire une activité NF-.kappa.B ou une apoptose.

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