C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 45/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2440930
The present invention provides novel polynucleotides encoding HGPRBMY14 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel HGPRBMY14 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
L'invention concerne des polynucléotides codant pour des polypeptides HGPRBMY, des fragments et des homologues de ces polypeptides. Elle concerne aussi des vecteurs, des cellules hôtes, des anticorps ainsi que des procédés de production, synthétiques et de recombinaison, de ces polypeptides. Elle concerne encore des procédés de diagnostics et thérapeutiques destinés à appliquer ces polypeptides HGPRBMY14 au diagnostic, au traitement et/ou à la prévention de maladies et/ou de troubles divers associés à ces polypeptides. Elle concerne enfin des procédés de criblage permettant d'identifier des agonistes et des antagonistes des polynucléotides et polypeptides de l'invention.
Barber Lauren
Cacace Angela
Feder John
Kornacker Michael
Nelson Thomas C.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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