C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/713 (2006.01) A61K 38/17 (2006.01) A61P 35/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 15/66 (2006.01) C12P 21/00 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2424014
The present invention describes a newly discovered human G-protein coupled receptor and its encoding polynucleotide. Also described are expression vectors, host cells, agonists, antagonists, antisense molecules, and antibodies associated with the polynucleotide and/or polypeptide of the present invention. In addition, methods for treating, diagnosing, preventing, and screening for disorders associated with aberrant cell growth, immunological diseases, neurological conditions, and diseases or disorders related to the spinal cord and brain, as well as breast and colon, are illustrated.
Cette invention a trait à un récepteur couplé à la protéine G humaine, récemment découvert, ainsi qu'au polynucléotide le codant. L'invention porte également sur des vecteurs d'expression, des agonistes, des antagonistes, des molécules antisens et des anticorps associés au polynucléotide et/ou au polypeptide susmentionnés. Elle concerne, de surcroît, des méthodes thérapeutiques, diagnostiques et prophylactiques, ainsi que des criblages relatifs à des troubles associés à une croissance cellulaire aberrante, à des maladies immunitaires, des troubles neurologiques ainsi qu'à des maladies ou des troubles en rapport avec la moelle épinière ou le cerveau, de même qu'avec la poitrine ou le côlon.
Barber Lauren
Battaglino Peter
Cacace Angela
Feder John N.
Hawken Donald R.
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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