A novel human gene similar to a secreted murine protein sdf5

Details A novel human gene similar to a secreted murine protein sdf5 A novel human gene similar to a secreted murine protein sdf5

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2224473

ATG-1622 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing ATG-1622 polypeptides and polynucleotides in the design of protocols for the treatment of heart disease, hypertension, kidney diseases, obesity, insulin resistance, diabetes, and CNS diseases, among others, and diagnostic assays for such conditions.

Polypeptides ATG-1622 et polynucléotides, et méthodes pour produire ces polypeptides à l'aide de techniques de recombinaison génétique. La présente invention concerne également des méthodes d'utilisation de polypeptides ATG-1622 et de polynucléotides dans l'élaboration de protocoles de traitement des cardiopathies, de l'hypertension, des néphropathies, de l'obésité, de l'insulinorésistance, du diabète et des maladies du SNC, entre autres, et d'épreuves servant au diagnostic de ces affections.

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