A novel human gene similar to a secreted murine protein sfrp-1

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/00 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2221836

ATG-1709 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing ATG-1709 polypeptides and polynucleotides in the design of protocols for the treatment of heart disease, hypertension, cardiovascular diseases, kidney diseases, obesity, insulin resistance, diabetes, and Central Nervous System (CNS) diseases., among others, and diagnostic assays for such conditions.

Polypeptides et polynucléotides ATG-1709, ainsi que méthodes de production de polypeptides par des techniques de recombinaison. Des méthodes d'utilisation des polypeptides et polynucléotides ATG-1709 sont également décrites en ce qui touche l'élaboration de protocoles pour le traitement des maladies du coeur, de l'hypertension, des maladies cardio-vasculaires, des maladies du rein, de l'obésité, de la résistance insulinique, du diabète et des maladies du système nerveux central (SNC), entre autres, ainsi que des méthodes diagnostiques pour de telles maladies.

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