A novel human gene similar to a secreted protein frizb...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 38/22 (2006.01) C07K 14/47 (2006.01) C07K 14/575 (2006.01) C07K 16/18 (2006.01) C07K 16/26 (2006.01) C12Q 1/68 (2006.01) G01N 33/567 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2221837

ATG-1639 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing ATG-1639 polypeptides and polynucleotides in the design of protocols for the treatment of heart disease, hypertension, cardiovascular diseases, kidney diseases, obesity, insulin resistance, diabetes, CNS diseases, additions., among others, and diagnostic assays for such conditions.

Polypeptides et polynucléotides ATG-1639, ainsi que méthodes de production de polypeptides par des techniques de recombinaison. Des méthodes d'utilisation des polypeptides et polynucléotides ATG-1639 sont également décrites en ce qui touche l'élaboration de protocoles pour le traitement des maladies du coeur, de l'hypertension, des maladies cardio-vasculaires, des maladies du rein, de l'obésité, de la résistance insulinique, du diabète, des maladies du système nerveux central (SNC) et des additions, entre autres, ainsi que des méthodes diagnostiques pour de telles maladies.

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