A novel human metabotropic glutamate receptor

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/62 (2006.01) C07K 14/705 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01) G01N 33/566 (2006.01) G01N 33/94 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2388514

A novel human metabotropic glutamate receptor (mGluR) protein is identified, sequenced, and cloned. The receptor may be used to screen for compounds that modulate the activity of the mGluR. The recombinant mGluR as well as compounds that modulate mGluR activity may be used in the diagnosis and treatment of neurological disorders and diseases.

L'invention concerne une nouvelle protéine réceptrice glutamate métabotropique humaine (mGluR) identifiée, séquencée et clonée. Ce récepteur peut servir à dépister des composés qui modulent l'activité de la mGluR. La mGluR recombinante, ainsi que des composés modulant l'activité de la mGluR, peuvent être employés afin de diagnostiquer et traiter troubles et affections neurologiques.

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