A novel intein and uses thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/55 (2006.01) C07K 14/37 (2006.01) C07K 14/39 (2006.01) C12Q 1/18 (2006.01)

Patent

CA 2450677

The invention provides a self-cleaving protein or intein. The intein can be obtained from a wide range of Cryptococcus neoformans. Also provided are methods of using the inteins such as in protein purification and as a target in testing the efficacy of drugs to inhibit intein function.

L'invention concerne une intéine ou une protéine à autoclivage. On peut obtenir cette intéine à partir d'une grande variété de <i>Cryptococcus néoformans</i>. Ladite invention concerne aussi des méthodes d'utilisation des intéines, telles que dans la purification protéique et en tant que cible dans l'essai de l'efficacité de médicaments destinés à inhiber la fonction de l'intéine.

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