C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/42 (2006.01) C12Q 1/48 (2006.01) C12N 9/12 (2006.01)
Patent
CA 2360581
The present invention provides a method for identifying inhibitors of protein kinases. Methods are also provided for inhibiting protein kinase activity. Specific non-peptide protein tyrosine kinase inhibitor are provided. The protein kinases produced using the method of the present invention may be used to treat a number of conditions in patients, including cancer, psoriasis, arthrosclerosis, or immune system activity.
La présente invention concerne un procédé permettant d'identifier des inhibiteurs de protéines kinase ; des procédés d'inhibition de l'activité des protéines kinase ; et des inhibiteurs de protéines tyrosine kinase non peptidiques spécifiques. Les protéines kinase produites à l'aide du procédé de la présente invention peuvent être utilisées pour traiter un certain nombre de pathologies chez des patients telles que le cancer, le psoriasis, l'arthrosclérose ou l'activité déréglée du système immunitaire.
Hangauer David G. Jr.
Marsilje Thomas H.
Milkiewicz Karen L.
Gowling Lafleur Henderson Llp
The Research Foundation Of State University Of New York
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