A novel method of protecting islet cells from apoptosis...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/11 (2006.01) A61K 31/7088 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2637137

The present invention relates to methods for improving the viability and recovery of islets that are separated from a donor organ for subsequent transplantation and more particularly relates to the use of eIF5A siRNAs to enhance the viability of islets.

La présente invention concerne des méthodes permettant d'améliorer la viabilité et la récupération d'îlots séparés d'un organe de donneur pour une greffe ultérieure et, plus particulièrement, l'utilisation d'ARNsi eIF5A afin d'améliorer la viabilité des îlots.

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