A novel pharmaceutical preparation for preeclampsia,...

A - Human Necessities – 61 – K

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A61K 38/46 (2006.01) A61K 38/48 (2006.01) A61P 9/12 (2006.01) A61P 15/00 (2006.01)

Patent

CA 2719102

A therapeutic agent for the treatment of toxemia, preeclampsia and eclampsia and the method for preparing the therapeutic agents is disclosed. The therapeutic agent is a stable pharmaceutical preparation containing, but not limited to, digestive/pancreatic enzymes. The therapeutic agent may be manufactured by a variety of encapsulation technologies. Delivery of the therapeutic agent may be made orally, through injection, by adherence of a medicated patch or other method. Further, a method of using of a biomarker, the presence of chymotrypsin in the maternal GI tract to determine the likelihood of developing preeclampsia, pregnancy induced hypertension, and eclampsia/toxemia is disclosed.

Linvention concerne un agent thérapeutique pour le traitement de la toxémie, de léclampsisme et de léclampsie et le procédé de préparation des agents thérapeutiques. Lagent thérapeutique est une préparation pharmaceutique stable contenant, sans s'y limiter, des enzymes digestives/pancréatiques. Lagent thérapeutique peut être fabriqué par une variété de technologies dencapsulation. Ladministration de lagent thérapeutique peut se faire par voie orale, par injection, par adhérence dun timbre médicamenteux ou un autre procédé. En outre, l'invention concerne l'utilisation d'un biomarqueur, ainsi que la présence de chymotrypsine dans le tractus intestinal maternel pour déterminer la probabilité de développer un éclampsisme, une hypertension induite par grossesse et une éclampsie/toxémie.

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