C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61P 13/08 (2006.01) A61P 35/00 (2006.01) C07H 21/02 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/435 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2362527
Disclosed are nucleic acid and amino acid sequences encoded by a novel, prostate specific gene (UC41) and diagnostic techniques for the detection of human prostate cancer utilizing such nucleic acid and amino acid sequences. Genetic probes and methods useful in monitoring the progression and diagnosis of prostate cancer are described. Methods of treatment for prostate cancer utilizing antisense constructs or antibodies specific for UC41 gene products are also described.
L'invention concerne des séquences d'acides nucléiques et amino-acides codées par un nouveau gène (UC41) spécifique à la prostate, ainsi que des méthodes diagnostiques de dépistage du cancer de la prostate humain à l'aide de ces séquences d'acides nucléiques et amino-acides. L'invention concerne également des sondes génétiques et des méthodes utilisées dans la surveillance de la progression et du diagnostic du cancer de prostate. L'invention concerne enfin des méthodes de traitement du cancer de la prostate à l'aide de produits de recombinaison antisens ou d'anticorps spécifiques aux produits géniques UC41.
An Gang
Veltri Robert
Goudreau Gage Dubuc
Laboratory Corporation Of America Holdings
Urocor Inc.
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