A novel receptor-type tyrosine kinase and use thereof

Details A novel receptor-type tyrosine kinase and use thereof A novel receptor-type tyrosine kinase and use thereof

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 38/45 (2006.01) C07K 14/71 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/12 (2006.01) C12P 21/00 (2006.01) C12Q 1/48 (2006.01) G01N 33/566 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2111006

The present invention relates to an isolated receptor-type tyrosine kinase, said tyrosine kinase characterised by, in its natu-rally occurring form, being reactive to monoclonal antibody III.A4, having an apparent molecular weight of approximately 120-150 kD in its glycosylated form and having an N-terminal amino acid sequence comprising E L I P Q P. More particularly, the present inventino relates to human eph/elk-like kinase (HEK).

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