C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 235/34 (2006.01) A61K 31/135 (2006.01) A61K 31/165 (2006.01) A61K 31/22 (2006.01) A61K 31/235 (2006.01) A61P 1/00 (2006.01) A61P 11/00 (2006.01) A61P 25/00 (2006.01) C07C 233/04 (2006.01) C07C 233/11 (2006.01) C07C 233/40 (2006.01)
Patent
CA 2293928
An object of the present invention to offer a novel substituted alkyltetraamine derivative which is useful as a tachykinin antagonist. This invention relates to a substituted alkyltetraamine derivative represented by the following formula (I) or a pharmaceutically acceptable salt, a complex compound or a solvate thereof. (see formula I) [In the formula, R1, R2, R3 and R4 are same or different and each of them is a phenyl group which may be substituted with one or more hydroxyl, lower alkoxy and/or acyloxy group(s).] The compound of the present invention is entirely different from the tachykinin antagonists is useful as anti-inflammatory agent, anti-allergic agent, analgesic, antiemetic, agent for irritable colon syndrome, agent for dermal disease, agent for vasospastic disease, agent for cerebral ischemic disease, antidepressant, antianxiety agent, agent for autoimmune disease, muscle relaxant, antispasmodic, etc.
Nakamura Ko
Otsuka Masanori
Yamamoto Atsushi
Kirby Eades Gale Baker
Nippon Zoki Pharmaceutical Co. Ltd.
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