A nucleic acid construct containing a nucleic acid derived...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/11 (2006.01) C12N 5/00 (2006.01) C12N 7/00 (2006.01) C12Q 1/06 (2006.01)

Patent

CA 2525698

A replicon RNA comprising a base sequence which contains at least 5~- nontranslational region, base sequences encoding NS3 protein, NS4A protein, NS4B protein, NS5A protein and NS5B protein and 3~-nontranslational region on the genomic RNA of hepatitis C virus of genotype 2a.

La présente invention concerne un réplicon d'ARN comprenant une séquence de base qui contient au moins une région none traductionnelle 5', des séquences de base codantes pour la protéine NS3, la protéine NS4A, la protéine NS5A et la protéine NS5B et une région non traductionnelle 3' de l'ARN génomique du virus de l'hépatite C de génotype 2a. ,

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