C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 45/00 (2006.01) C07K 1/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/00 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) G01N 33/566 (2006.01) G01N 33/567 (2006.01)
Patent
CA 2473707
Provided herein is a novel and useful G-protein coupled receptor that is involved in signal transduction with respect to inflammation and physiological immunological response. Also provided are methods of using the receptor to screen for molecules that may modulate the activity of the receptor. Such molecules may readily have applications in treating a plethora of inflammation and immunologically related diseases and disorders.
La présente invention concerne un récepteur couplé à la protéine G nouveau et utile impliqué dans la transduction du signal par rapport à l'inflammation et à la réponse immunologique physiologique. L'invention concerne également des procédés d'utilisation du récepteur pour le criblage de molécules susceptibles de moduler l'activité du récepteur. De telles molécules peuvent aisément trouver des applications dans une grande variété de maladies et de troubles liés à l'inflammation et aux mécanismes immunitaires
Cai Jidong
Eishingdrelo Haifeng
Sandrasagra Anthony
Aventis Pharmaceuticals Inc.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
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