A nucleic acid encoding a g-protein-coupled receptor, and...

Details A nucleic acid encoding a g-protein-coupled receptor, and... A nucleic acid encoding a g-protein-coupled receptor, and...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 45/00 (2006.01) C07H 21/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12P 21/02 (2006.01) G01N 33/50 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2476239

Provided herein is a novel and useful G-protein coupled receptor that is involved in signal transduction with respect to inflammation and physiological immunological response. Also provided are methods of using the receptor to screen for molecules that may modulate the activity of the receptor. Such molecules may readily have applications in treating a plethora of inflammation and immunologically related diseases and disorders.

L'invention porte sur un récepteur nouveau et utile couplé à la protéine G, qui est impliqué dans une transduction de signal en cas de réponse inflammatoire et de réponse immunologique et physiologique. L'invention concerne aussi des procédés d'utilisation de ce récepteur dans le criblage des molécules susceptibles de moduler l'activité du récepteur. De telles molécules peuvent rapidement trouver des applications dans le traitement de nombreuses inflammations et de maladies et de troubles immunologiques.

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