A pax-encoding vector and use thereof

Details A pax-encoding vector and use thereof A pax-encoding vector and use thereof

C - Chemistry, Metallurgy

12

N

C12N 15/79 (2006.01) C12N 5/077 (2010.01) A61K 35/12 (2006.01) A61K 35/34 (2006.01) A61K 48/00 (2006.01) C12N 15/12 (2006.01) C12N 15/85 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2357403

The present invention provides a Pax-encoding vector that comprises a sequence encoding a Pax7, Pax3 or an active variant or fragment thereof, which can be used to induce myogenic differentiation of adult pluripotent stem cells. The present invention further pertains to methods of preparing the Pax-encoding vector. Also provided is a method of inducing myogenic differentiation of adult pluripotent stem cells.

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