A peg-albumin composition having at least one protected...

Details A peg-albumin composition having at least one protected... A peg-albumin composition having at least one protected...

A - Human Necessities

61

K

A61K 47/48 (2006.01) C08L 71/02 (2006.01) C08L 89/00 (2006.01)

Patent

CA 2754395

This composition comprises a polyethylene glycol-albumin composition having at least one protected thiol region wherein the composition comprises PEG-AlbCys34 with Cys-34 preserved as a thiol. The albumin is linked to medications such as, antioxidants with a reduced sulfhydryl group through the Cys 34 residing on the albumin. The compositions are useful in treating patients.

Cette composition comprend une composition polyéthylène glycol-albumine ayant au moins une région thiol protégée, la composition comprenant PEG-AlbCys34 avec Cys 34 préservé en tant que thiol. L'albumine est liée à des médicaments tels que des antioxydants avec un groupe sulfhydryle réduit par l'intermédiaire de la Cys 34 située sur l'albumine. Les compositions sont utiles dans le traitement de patients.

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