A perfusion assessment method and system based on bolus...

A - Human Necessities – 61 – B

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A61B 8/06 (2006.01) A61B 8/00 (2006.01)

Patent

CA 2588182

A perfusion assessment system (105) is proposed. The system includes means (705-735) for providing an echo-power signal indicative of a perfusion of a contrast agent in a body-part under analysis, the contrast agent being administered as a bolus and undergoing a significant destruction during a passage of the contrast agent in the body- part, means (740;755-767) for associating the echo-power signal to a model function including the product between a bolus function indicative of the passage of the contrast agent without said destruction and a reperfusion function indicative of a reperfusion of the contrast agent in the body part following the destruction corresponding to a substantially constant inflow of the contrast agent, and means (738;743) for estimating at least one perfusion indicator from the bolus function and/or the reperfusion function.

L'invention concerne un système d'évaluation de perfusion (105). Ce système comprend un moyen (705-735) permettant de délivrer un signal puissance d'écho indiquant, pour une perfusion, un agent de contraste dans une partie d'un organisme soumise à une analyse, l'agent de contraste étant administré comme un bolus et étant soumis à une destruction importante lorsque l'agent de contraste passe dans la partie d'organisme. Ce système comprend également un moyen (740;755-767) permettant d'associer le signal puissance d'écho à une fonction modèle incluant le produit entre une fonction bolus indiquant le passage de l'agent de contraste sans cette destruction et une fonction de reperfusion indiquant une reperfusion de l'agent de contraste dans la partie d'organisme à la suite de la destruction correspondant à un afflux sensiblement constant de l'agent de contraste. Ce système comprend enfin un moyen (738;743) permettant d'évaluer au moins une perfusion donnant une indication de la fonction bolus et/ou de la fonction de reperfusion.

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