A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/26 (2006.01) A61K 31/4704 (2006.01) A61K 47/02 (2006.01)
Patent
CA 2725487
An object of the present invention is to provide a pharmaceutical composition containing rebamipide, which is unnecessary to be re-dispersed, has an enough transparency, and exhibits neutral to weakly acidic pH not to injure the keratoconjunctiva of a patient suffering from dry eye. The present pharmaceutical composition comprises (1) rebamipide, (2) an amino sugar, and (3) an buffer agent, which has no inorganic cation.
Un objet de la présente invention est de fournir une composition pharmaceutique contenant du rébamipide, ne nécessitant pas de redispersion supplémentaire et présentant une transparence suffisante et un pH neutre ou faiblement acide permettant de ne pas léser la cornée et la conjonctive dun patient souffrant de sécheresse oculaire. La présente composition pharmaceutique contient (1) du rébamipide, (2) un sucre aminé et (3) un agent tampon ne renfermant aucun cation inorganique.
Ishikawa Shinichi
Sumida Shun-Ichiro
Kirby Eades Gale Baker
Otsuka Pharmaceutical Co. Ltd.
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