A pharmaceutical composition for inhibiting non-intentional...

A - Human Necessities – 61 – K

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A61K 31/662 (2006.01) A61K 31/00 (2006.01) A61K 31/197 (2006.01) A61K 31/42 (2006.01) A61K 31/437 (2006.01) A61K 31/4409 (2006.01) A61K 31/498 (2006.01) A61K 31/5513 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2342435

It is an object of the present invention to provide a pharmaceutical composition, which permits the inhibition of nori-intentional motions such as poriomania and hyperkinesia without any inhibition of intentional motions and in particular to provide a pharmaceutical composition capable of treating patients suffering from, for instance, poriomania and hyperkinesia. Moreover, it is also an object of the present invention to provide a method of using running neuron-inhibitory substances. A pharmaceutical composition for treating a patient suffering from symptoms accompanied by non-intentional motions such as poriomania and hyperkinesia, comprising a substance capable of pre-synaptically or post- synaptically inhibiting the running neurons. A method of using such substances permits the preparation of a pharmaceutical composition for treating a patient suffering from symptoms accompanied with unintentional motions such as poriomania and hyperkinesia. In particular, the pharmaceutical composition comprises a member selected from the group consisting of GABA B receptor agonists, GABA A receptor agonists, and GABA A receptor-enhancing substances, or any combination thereof. Moreover, the foregoing problems can likewise be solved by providing a method of using such running neuron-inhibitory substances, which permits the preparation of a pharmaceutical composition for treating a patient suffering from the foregoing symptoms.

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