A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/426 (2006.01) A61K 31/663 (2006.01) A61P 19/10 (2006.01)
Patent
CA 2732864
The present invention provides a pharmaceutical composition for preventing or treating osteoporosis, comprising a benzamidine derivative or salt thereof and bisphosphonate for the purpose of using simultaneously, separately, or sequentially as active ingredients. As a prophylactic or therapeutic composition for osteoporosis, the combination treatment of the benzamidine derivative and the bisphosphonate compound exhibits excellent inhibitory effect on osteoclast differentiation than the total effect of each individual treatment, thereby being used for the prevention or treatment of osteoporosis.
La présente invention concerne une composition pharmaceutique pour prévenir ou traiter l'ostéoporose, qui comprend un dérivé de benzamidine ou un sel de celui-ci et du bisphosphonate pour une utilisation combinée, séparée ou séquentielle en tant que principes actifs. En tant que composition prophylactique ou thérapeutique pour l'ostéoporose, le traitement combiné à base du dérivé de benzamidine et du composé bisphosphonate permet d'assurer un excellent effet inhibiteur sur la différenciation des ostéoclastes par comparaison à l'effet total de chaque traitement individuel, ce qui s'avère être utile pour prévenir ou traiter l'ostéoporose.
Hwang Yun Ha
Jin Young Goo
Kim Ki Yoon
Lee Jin Soo
Ryu Jei Man
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Dong Wha Pharmaceutical Co. Ltd.
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