A pharmaceutical composition for the prevention and...

Details A pharmaceutical composition for the prevention and... A pharmaceutical composition for the prevention and...

A - Human Necessities

61

K

A61K 31/52 (2006.01) A61K 31/403 (2006.01) A61K 31/4155 (2006.01) A61K 31/4178 (2006.01) A61K 31/519 (2006.01) A61K 31/53 (2006.01) A61K 31/5355 (2006.01) A61P 25/30 (2006.01)

Patent

CA 2536280

Pharmaceutical compositions are disclosed for the treatment of alcohol or cocaine dependence or addiction, tobacco dependence or addiction, reduction of alcohol withdrawal symptoms or aiding in the cessation or lessening of alcohol use or substance abuse or other behavioral dependencies including gambling. The pharmaceutical compositions are comprised of a therapeutically effective combination of an opioid receptor antagonist and a CB-1 receptor antagonist and a pharmaceutically acceptable carrier. The method of using these compounds is also disclosed.

L'invention concerne des compositions pharmaceutiques pour le traitement de la dépendance ou de l'accoutumance à l'alcool ou à la cocaïne, au tabac, la réduction des symptômes du sevrage alcoolique ou bien l'aide à l'arrêt ou à la diminution de la consommation d'alcool ou de l'usage de substances toxiques ou encore d'autres dépendances comportementales, notamment le jeu. Ces compositions pharmaceutiques sont constituées d'une association thérapeutiquement efficace d'un antagoniste du récepteur opioïde, d'un antagoniste du récepteur CB-1 et d'un excipient pharmaceutiquement acceptable. L'invention concerne également une méthode d'utilisation de ces composés .

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