A pharmaceutical composition for the prevention and...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/00 (2006.01) A61K 45/06 (2006.01) A61P 25/30 (2006.01) A61P 25/32 (2006.01) A61P 25/34 (2006.01)

Patent

CA 2535811

Pharmaceutical compositions are disclosed for the treatment of alcohol or cocaine dependence or addiction, alcohol dependence or addiction, reduction of alcohol withdrawal symptoms or aiding in the cessation or lessening of tobacco use or substance abuse or other behavioral dependencies. The pharmaceutical compositions are comprised of a therapeutically effective combination of a nicotinic receptor partial agonist and an alpha2delta ligand and a pharmaceutically acceptable carrier. The method of using these compounds is also disclosed.

L'invention concerne des compositions pharmaceutiques pour le traitement de la dépendance ou de l'accoutumance à l'alcool ou à la cocaïne, au tabac, la réduction des symptômes du sevrage alcoolique ou bien l'aide à l'arrêt ou à la diminution du tabagisme ou de l'usage de substances toxiques ou encore d'autres dépendances comportementales. Ces compositions pharmaceutiques sont constituées d'une association thérapeutiquement efficace d'un agoniste partiel du récepteur nicotinique, d'un ligand alpha2delta et d'un excipient pharmaceutiquement acceptable. La méthode d'utilisation de ces composés est également décrite.

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