A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/137 (2006.01) A61K 9/00 (2006.01) A61K 31/135 (2006.01) A61K 47/32 (2006.01)
Patent
CA 2303339
The present invention teaches a composition comprising a .beta.-adrenergic agonist in a bioadhesive carrier. Preferably, the composition comprises terbutaline in polycarbophil. The present invention additionally teaches the local administration of a .beta.-adrenergic agonist for the purpose of treating or preventing dysmenorrhea or premature labor. Using this composition and the method of treatment provides sufficient local levels of the drug to provide therapeutic efficacy, but avoids many untoward adverse events.
La présente invention concerne une composition comprenant un agoniste d'adrénergique beta dans un excipient bioadhésif. De préférence la composition comprend de la Terbutaline dans un polycarbophile. La présente invention concerne également l'administration locale d'un agoniste d'adrénergique beta afin de traiter une dysménorrhée ou un accouchement prématuré. L'utilisation de cette composition et de la méthode de traitement permet d'obtenir des niveaux locaux suffisants du médicament pour produire une efficacité thérapeutique, et d'éviter beaucoup d'effets indésirables.
Bologna William J.
de Ziegler Dominique
Levine Howard L.
Columbia Laboratories (bermuda) Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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