C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/24 (2006.01) A61K 31/40 (2006.01)
Patent
CA 2056067
A physical form of N-[4-[5-(cyclopentyloxycarbonyl)- amino-1-methyl-indol-3-ylmethyl]-3-methoxybenzoyl]-2-methylbenzene- sulphonamide substantially free of other physical forms, which form is crystalline, has an X-ray powder diffraction pattern with specific peaks occuring at 2~~8.1, 13.7, 16.4, 20.5 and 23.7° and an infra-red spectrum (0.5% in KBr) having sharp peaks at 3370, 1670, 1525, 1490, 1280, 890, 870 and 550 cm-1, end a melting point in the range of 190° to 200°C, a process for its preparation and pharmaceutical compositions containing it. Also disclosed is a flovable preparation of the physical form which is in the form of soft pellets, and a process for obtaining this preparation.
Edwards Martin P.
Sherwood John D.
Astrazeneca Uk Limited
Edwards Martin P.
Fetherstonhaugh & Co.
Sherwood John D.
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