C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/00 (2006.01) C12N 9/10 (2006.01)
Patent
CA 2342831
In various aspects, the present invention provides nucleic acid sequence encoding all or part of a new plant long chain fatty acid condensing enzyme (a fatty acid elongase), designated herein as KCS2 (for beta-ketoacyl-coenzyme A synthase 2). In some embodiments, KCS2 may mediate the biosynthesis of C18, C20, C22 and C24 fatty acids. The activity of the enzyme is typically characterized by two carbon (malonyl-CoA) additions to C16, C18, C20 and C22 moieties (C16-C22 acyl CoA molecules), i.e. condensation of malonyl-CoA with a C16, C18, C20 or C22 acyl-CoA. The fatty acids produced by the enzyme may for example be saturated 18:0, 20:0, 22:0 and 24:0 fatty acids. The invention includes recombinant nucleic acid molecules comprising a heterologous nucleic acid coding sequence encoding the plant long chain fatty acid condensing enzyme.
Selon divers aspects, la présente invention concerne une séquence d'acides nucléiques codant tout ou partie d'une nouvelle enzyme condensant les acides gras à chaînes longues (élongase d'acide gras), désignée ci-après KCS2 (pour béta-kétoacyl-coenzyme A synthase 2). Dans certains modes de réalisation, KCS2 peut induire la biosynthèse d'acides gras C18, C20, C22 et C24. L'activité de cette enzyme est généralement caractérisée par les additions de deux carbone(malonyl-CoA) aux fractions C16, C18, C20 et C22 (molécules acylCoA C16-C22), c'est-à-dire, la condensation de malonyl-CoA avec un acyl-CoA C16, C18, C20 ou C22. Les acides gras produits par l'enzyme peuvent, par exemple, être des acides gras 18 :0, 20 :0, 22 :0 et 24 :0 saturés. L'invention concerne des molécules d'acide nucléique de recombinaison comprenant une séquence de codage d'acides nucléiques hétérologues codant l'enzyme de condensation d'acides gras à chaînes longues de plantes.
Clemens Sabine
Kunst Ljerka
Smart & Biggar
The University Of British Columbia
LandOfFree
A plant long chain fatty acid biosynthetic enzyme does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with A plant long chain fatty acid biosynthetic enzyme, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and A plant long chain fatty acid biosynthetic enzyme will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1943149