A polymer micelle as monolayer or layer-laminated surface

Details A polymer micelle as monolayer or layer-laminated surface A polymer micelle as monolayer or layer-laminated surface

A - Human Necessities

61

L

A61L 31/10 (2006.01)

Patent

CA 2389917

The present invention is directed to a coated biomedical device said micelle having a hydrophilic outer shell and a hydrophobic inner core, or a hydrophobic outer shell and a hydrophilic inner core said micelle comprised of a block copolymer having a HLB value ranging from about 1 to about 40. The medical device may have one coating thereon or multiple coatings. The present invention is also directed to the use of the micelle as a drug carrier.

L'invention concerne un dispositif biomédical revêtu, le revêtement comprenant une micelle ayant une coquille extérieure hydrophile et un noyau intérieur hydrophobe, ou une coquille extérieure hydrophobe et un noyau intérieur hydrophile. La micelle est constituée d'un copolymère bloc dont la valeur HLB est comprise entre 1 et 40. Le dispositif médical peut comporter une ou plusieurs couches de revêtement. L'invention concerne également l'utilisation de la micelle comme vecteur de médicament.

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