A polymer with superior polar retention for sample pretreatment

B - Operations – Transporting – 01 – J

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B01J 20/26 (2006.01) B01J 20/28 (2006.01) B01J 20/285 (2006.01) B01J 20/32 (2006.01) B01J 37/06 (2006.01) C08F 8/30 (2006.01) C08F 12/04 (2006.01) G01N 30/50 (2006.01) G01N 1/34 (2006.01)

Patent

CA 2487092

A polymeric sorbent that can be employed in the extraction and purification of polar and nonpolar molecules from a complex media (e.g. pharmaceuticals from biological matrices) by solid phase extraction (SPE). The sorbent exhibits a strong capacity for the retention of polar molecules and can facilitate the recovery of compounds possessing a range of polarities while furnishing clean extracts showing low ion suppression. The polymer is wettable and remains wetted over long periods of time.

L'invention concerne un sorbant polymère pouvant être utilisé dans l'extraction et la purification de molécules polaires et non polaires provenant d'un support complexe (par exemple des produits pharmaceutiques issus de matrices biologiques) par extraction en phase solide (SPE). Ce sorbant présente une forte capacité de rétention de molécules polaires et peut faciliter la récupération de composés possédant une plage de polarités tout en fournissant des extraits propres à faible suppression ionique. Le polymère est mouillable et reste mouillé pendant de longues périodes temporelles.

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