A polypeptide-polymer conjugate

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/96 (2006.01) A61K 8/66 (2006.01) A61K 8/86 (2006.01) A61K 8/90 (2006.01) A61K 47/48 (2006.01) A61Q 5/02 (2006.01) A61Q 5/10 (2006.01) A61Q 5/12 (2006.01) A61Q 9/02 (2006.01) A61Q 19/00 (2006.01) A61Q 19/10 (2006.01) C11D 3/37 (2006.01) C11D 3/38 (2006.01) C11D 3/386 (2006.01) C12N 9/54 (2006.01)

Patent

CA 2332334

The present invention relates to a polypeptide-polymer conjugate having coupled one or more polymers covalently to the parent polypeptide, wherein the polymer is characterized by general formula: EOxPOy (I) wherein x=1-99 %, y=1- 99 %, and x+y=100 %. The invention also relates to industrial compositions and products comprising a conjugate of the invention and to the use of said conjugate for reducing the allergenicity of industrial compositions and products such as skin care products and detergents compositions.

La présente invention concerne un conjugué polypeptide-polymère comportant un ou plusieurs polymères couplés de manière covalente au polypeptide précurseur, le polymère étant caractérisé par la formule générale EO¿x?PO¿y? (I) dans laquelle x=1-99 %, y=1-99 % et x + y=100 %. L'invention concerne également des compositions et produits industriels comprenant un conjugué de l'invention, ainsi que l'utilisation de ce conjugué pour réduire l'effet allergisant de compositions et produits industriels tels que des produits cosmétiques et des compositions détergentes.

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