A polypeptide vector for the delivery of immunogenic...

Details A polypeptide vector for the delivery of immunogenic... A polypeptide vector for the delivery of immunogenic...

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 9/00 (2006.01) A61K 39/385 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01) C07K 14/00 (2006.01)

Patent

CA 2228822

Within an engineered polypeptide-based vector for the delivery of immunogenic epitopes or drugs to the immune system, there is a helix-loop-helix motif combined with a endoplasmic reticulum (ER) retrieval signal, glycosylation motif and a protease-specific motif subtended by a disulfide bond. It carries peptide epitopes and other drugs through attachment to the N-terminus of the vector. The primary structure of the vector is : WCSRAVRRYCG-(-VAKLADA-)n-VPTTANNFG-(-VAKLADA-)n-GGKDEL

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