A potential effector for the grb7 family of signalling proteins

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/11 (2006.01) C07K 14/46 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2303760

A novel polynucleotide molecule is disclosed which encodes a candidate effector protein for the Grb7 family of signalling proteins. Detection of the protein in a sample such as a homogenised tissue sample should provide a useful tumour marker and/or prognostic indicator for certain human cancers such as breast and prostate cancer.

L'invention concerne une molécule polynucléotidique qui code pour une protéine effectrice candidate se liant à la famille Grb7 des protéines de signalisation. La détection de ladite protéine dans un échantillon, tel qu'un échantillon tissulaire homogénéisé, devrait être utile comme marqueur tumoral et/ou indicateur pronostique pour certains cancers humains, cancer du sein ou de la prostate par exemple.

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