C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/64 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2609435
The present invention relates to a recombinant method of production of activated Protein C. The invention relates to a method of construction, transformation, expression, purification and production of recombinant activated human protein C. DNA constructs comprising the control elements associated with the gene of interest has been disclosed. The nucleic acid sequence of interest has been codon optimized to permit expression in the suitable mammalian host cells.
L'invention concerne une méthode recombinante de production d'une protéine C activée. L'invention concerne une méthode de construction, de transformation, d'expression, de purification et de production d'une protéine C humaine activée recombinante. Des constructions d'ADN comprenant des éléments de commande associés au gène de l'invention sont décrites. La séquence d'acide nucléique de l'invention a été optimisée au niveau de ses codons pour permettre son expression dans des cellules hôtes de mammifères appropriées.
Avestha Gengraine Technologies Pvt Ltd.
Avesthagen Limited
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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