A process for discriminating between biological states based...

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G01N 33/48 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2415775

The invention describes a process for determining a biological state through the discovery and analysis of hidden or non-obvious, discriminatory biological data patterns. The biological data can be from health data, clinical data, or from a biological sample, (e.g., a biological sample from a human, e.g., serum, blood, saliva, plasma, nipple aspirants, synovial fluids, cerebrospinal fluids, sweat, urine, fecal matter, tears, bronchial lavage, swabbings, needle aspirantas, semen, vaginal fluids, pre-ejaculate.), etc. which is analyzed to determine the biological state of the donor. The biological state can be a pathologic diagnosis, toxicity state, efficacy of a drug, prognosis of a disease, etc. Specifically, the invention concerns processes that discover hidden discriminatory biological data patterns (e.g., patterns of protein expression in a serum sample that classify the biological state of an organ) that describe biological states.

L'invention concerne un procédé de détermination d'un état biologique par la découverte et l'analyse de types de données biologiques discriminatoires cachés ou non évidents. Les données biologiques peuvent provenir de données de santé, de données cliniques ou d'un échantillon biologique (par exemple un échantillon biologique tiré d'un sujet humain, par exemple, du sérum, du sang, de la salive, du plasma, de produits d'aspiration du mamelon, de liquides synoviaux, de la transpiration, de l'urine, des matières fécales, des larmes, d'un lavage bronchique, d'écouvillonnages, d'échantillons prélevés par aiguille, de sperme, de liquides vaginaux, d'un pré-éjaculat), etc., lequel est analysé afin de déterminer l'état biologique du donneur. L'état biologique peut être un diagnostic pathologique, un état de toxicité, l'efficacité d'un médicament, le pronostic d'une maladie, etc. Spécifiquement, l'invention concerne des procédés découvrant des types de données biologiques discriminatoires cachés (par exemple, des types d'expression de protéine dans un échantillon de sérum classifiant l'état biologique d'un organe) décrivant des états biologiques.

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