A process for preparing a controlled release composition

Details A process for preparing a controlled release composition A process for preparing a controlled release composition

A - Human Necessities

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A61K 9/22 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/30 (2006.01) A61K 9/52 (2006.01) A61K 31/19 (2006.01) A61K 31/196 (2006.01) A61K 31/275 (2006.01) A61K 31/277 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2242552

A process for preparing a controlled release composition with a controlled release matrix and containing a pharmaceutically active ingredient, which comprises granulating the active ingredient with a molten matrix material or with a matrixmaterial while it is being melted and with optional additional inactive materials at a first elevated temperature, then cooling and screening the granulate, forming a fluidized bed of the resulting material at a second elevated temperature, and recovering the resulting product; and the product formed by the process.

Divulgation d'un processus de préparation d'une composition à libération contrôlée avec une matrice à libération contrôlée et contenant un ingrédient pharmaceutiquement actif, qui consiste en la granulation de l'ingrédient actif avec une matière matricielle fondue ou en train de fondre et, optionnellement, avec des matières inactives additionnelles à une première température élevée, puis à refroidir et à tamiser le granulat, formant un lit fluidisé de la matière résultante à une seconde température élevée, et à récupérer le produit résultant; ainsi que du produit formé par le processus.

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