C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 281/18 (2006.01) C07C 323/63 (2006.01) C07D 249/14 (2006.01)
Patent
CA 2337280
The present invention provides a process for preparing a compound of the general formula (I): (see formula I) wherein R1 to R5 are independently selected from hydrogen, halogen, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl or C1-6 alkoxy, all optionally substituted by one or more of halogen, hydroxy and aryl groups, as well as being independently selected from amino, mono- or disubstituted amino, alkenyloxy, acyl, acyloxy, cyano, nitro, aryl and alkylthio groups, which process comprises reacting a compound of the general formula (II): Image wherein R1 to R5 are as defined in formula (I), with aminoguanidine bicarbonate in a mixture of a water-soluble solvent and polyphosphoric acid.
Kaspi Joseph
Lexner Jael
Nadaka Vladimir
Chemagis Ltd.
Ridout & Maybee Llp
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