A process for producing an epoxy compound, a flavor and...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 303/04 (2006.01) A23L 1/226 (2006.01) A23L 2/56 (2006.01) A61K 8/31 (2006.01) A61K 8/33 (2006.01) A61K 8/34 (2006.01) A61K 8/35 (2006.01) A61K 8/92 (2006.01) A61Q 13/00 (2006.01) C07D 301/26 (2006.01)

Patent

CA 2390156

A process for the preparation of compounds of general formula (4): (4) (wherein R1 is alkyl having 5 or fewer carbon atoms, alkenyl, or the like); and aromatic compositions containing the compounds. A compound of general formula (4) is prepared by subjecting a compound of general formula (1): (1) (wherein X1 is chloro, bromo, or iodo) to Grignard reaction with R1MgX1, hydrolyzing the obtained compound to form a compound of general formula (3): (3) and reacting this compound with a base in the presence of a phase transfer catalyst.

L'invention concerne un procédé de préparation de composés correspondant à la formule (4), dans laquelle R?1¿ représente un alkyle possédant au maximum 5 atomes de carbone, un alcényle ou un groupe analogue, ainsi que des compositions aromatiques contenant ces composés. On obtient un composé correspondant à la formule générale (4) en soumettant un composé correspondant à la formule générale (1) (dans laquelle X?1¿ représente chloro, bromo ou iodo) à une réaction de Grignard avec R?1¿MgX?1¿, en hydrolysant le composé obtenu pour former un composé correspondant à la formule générale (3), et en faisant réagir ce composé avec une base, en présence d'un catalyseur de transfert de phase.

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